Our story began in 1919, when English-born pharmacist and chemist Frederick Alfred Upsher Smith started a company to refine digitalis. Working from a laboratory in downtown Minneapolis, his innovations helped thousands of people struggling with cardiac disease.

100 years later, we at Upsher-Smith Laboratories, LLC are still carrying out our original founder’s commitment to help improve the health and lives of patients. Now a part of Sawai Pharmaceutical, Co., Ltd., we offer a broad array of generic and branded medications, and our portfolio continues to grow. We know that our customers have many options to choose from in the marketplace, but we believe they repeatedly choose us because we go above and beyond—striving for uninterrupted supply, quick delivery and in-depth account and patient knowledge.

Upsher-Smith is a growing pharmaceutical company with expertise ranging from early-stage research to delivering on-market products.
Celebrating its 100-year anniversary, Upsher-Smith has grown to become a trusted U.S. pharmaceutical company.
Our long-standing commitment to high standards of quality and ethics is key to our success. These characteristics inspire trust and confidence on the part of the people who prescribe and benefit from our products.
Pharmacy has always been at our very foundation.
A respected pharmaceutical company at your service.
Employee diversity makes us stronger.
Upsher-Smith makes community involvement a priority.
Upsher-Smith has a long-standing tradition of funding external, independent, not-for-profit organizations in an effort to simplify access to treatment and deliver better health outcomes. The support we provide is aligned with our efforts to provide therapies and solutions which measurably improve individuals’ lives.
Get to know more about Upsher-Smith and our corporate locations in Minneapolis, Denver, and Morristown, where we embrace innovative solutions to meet the ever-increasing demands for work/life balance.
Sawai's corporate headquarters are in Osaka, Japan.
We follow a strict code of business conduct, and make sure our practices are in accordance with that code.
Upsher-Smith offers unparalleled opportunities for personal and professional growth in a wide array of careers. We’re looking for achievers and leaders who are passionate and exceptional people. In return, we offer a range of employee benefits in an environment that is challenging, stimulating, and rewarding.